Immediate-type hypersensitivity drug reactions

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immediate type drug hypersensitivity reactions and associated risk factors in an adult turkish men population

the study aimed to assess the prevalence and associated risk factors of immediate-type hypersensitivity reactions (hrs) to drugs in workers. the data consisted of 1152 questionnaires obtained from adult men that consisted of questions on hrs induced by drugs. the prevalence of self-reported drug hrs was 3.6% for all reactions. hrs were most common to beta-lactam antibiotics (51.2%) followed by ...

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Evaluation of type I drug hypersensitivity reactions caused by chemotherapy in hospitalized children

Background and Objective: Type I drug hypersensitivity reactions causes immune responses that could endanger life. Therefore this study was designed with the aim of evaluation and register reactions that caused by chemotherapy in hospitalized children in Rasoul Akram Hospital in 2015. Methods: This is a descriptive, cross sectional study. All statistical calculation was performed using the v...

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Prevalence of confirmed immediate type drug hypersensitivity reactions among school children.

BACKGROUND Despite drug-related hypersensitivity reactions are an important health problem, epidemiologic data on drug allergy and hypersensitivity are limited, and studies including diagnostic work-up are scarce. The aim of this study was to determine the actual frequency of immediate type drug hypersensitivity using diagnostic tests in school children with parent-reported drug allergies. ME...

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Basophil Reactivity as Biomarker in Immediate Drug Hypersensitivity Reactions—Potential and Limitations

Immediate drug hypersensitivity reactions (DHRs) resemble typical immunoglobulin E (IgE)-mediated symptoms. Clinical manifestations range from local skin reactions, gastrointestinal and/or respiratory symptoms to severe systemic involvement with potential fatal outcome. Depending on the substance group of the eliciting drug the correct diagnosis is a major challenge. Skin testing and in vitro d...

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The role of patch testing in non-immediate drug hypersensitivity reactions

Methods Herein we present case series of various non-immediate DHRs (occurring at any time as from 1 hour after the initial drug administration) amongst which drug-related intertriginous and flexural exanthema (Baboon syndrome), DRESS syndrome, fixed drug eruption and contact dermatitis. In all cases we performed patch testing with standardized and allergens prepared at our laboratory with the ...

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ژورنال

عنوان ژورنال: British Journal of Clinical Pharmacology

سال: 2014

ISSN: 0306-5251

DOI: 10.1111/bcp.12297